This also means that as far as James Bond's original movie canon is concerned, he never had his heart broken by Vesper Lynd. Since this was Bond's canonical first meeting with Leiter in the movies, there's no way they met at the casino in Royale-les-Eaux, France.
No, Bond had never met Felix Leiter (Jack Lord) before the CIA agent introduced himself at gunpoint to 007 in Jamaica. This timeframe does nod to Casino Royale's 1953 publication date, which happened 9 years prior to Dr. No began, James Bond ( Sean Connery) was already one of the British Secret Service's top Double-0 agents for about a decade. No is canonically Bond's first movie appearance, the events of the inaugural 007 film set the stage for everything that followed - but did the events of Casino Royale occur off-screen anyway? The answer is probably not. Related: James Bond's Correct Movie Order (Based On The Books)